Magnesium-L-Ascorbyl-Phosphate the most powerful form of Vitamin C is in all the DermCareMD Anti Aging Skin Care products and Treatments
Magnesium-L-Ascorbyl-Phosphate the most powerful form of Vitamin C is in all the DermCareMD Anti Aging Skin Care products and Treatments
Vitamin C comes in a number of forms. Of these, magnesium-l-ascorbyl-phosphate, or MAP, is the most effective, stable and skin-healthy of all forms of the vitamin.
Magnesium-L-Ascorbyl-Phosphate
• Increases of the longevity of skin cells by 150%.
• Is a potent antioxidant and inhibits lipid (fat) peroxidation unlike ascorbyl palmitate (c-ester, ester-c)that causes lipid peroxidation and kills skin cells when topically applied to skin and exposed tosunlight.
• Increases glucosaminoglycan (GAG: including collagen and hyaluronic acid) synthesis.
• Protects against harm caused by UV-B radiation.
• Is 1000 times less acid than ascorbic acid, vitamin C.
• Is very stable long-term, unlike ascorbic acid.• Safe and non-irritating; it has been used on the eye to heal corneal ulcers.
• Reduces skin hyperpigmentation (liver spots).
• Increases longevity of skin cells 150%
That sounds like science fiction! But it is real, and available now. Let us explain.It starts with your chromosomes. The 23 pairs of chromosomes contain all your 30,000+ genes. Eachchromosome is made up of two mirror image strands that have the appearance of a twisted ladder. There arefour different nucleic acids (two pairs); one mates only with its mirror image from the pair in thecorresponding site of that gene, on the other parallel ladder strand of DNA.
When a cell divides, each strand of each of the 23 pairs of chromosomes separate like an open zipper. This biological process is called mitosis. As the cell divides in half, 23 pairs of single stranded ("unzipped")chromosomes go into each new "daughter cell". To complete this process, each "unzipped" chromosomerecreates its missing mirror image strand by the "mating" with each nucleic acid of its counterpart, buildingthe missing side of the parallel strand of DNA for that chromosome.
Now you have a fully functioning cell, almost, except that the exposed ends of each chromosome become frayed after dividing and little pieces break off witheach of the cell divisions. The exposed ends of each chromosome are called telomeres. Genes are lost withthese tiny fragments at each cell division. This eventually limits the number of cell to the point where itcannot sustain further divisions and remain alive. This has been referred to as Hayflick's Limit called loss ofproliferation ability and premature senescence, and it is a serious undisclosed danger of all methods of skinexfoliation.
Magnesium-L-Ascorbyl-Phosphate
With the topical use of magnesium-l-ascorbyl-phosphate form of vitamin C (found in all of the DermCareMD anti aging skin care products and treatments), the telomeres can survive,allowing for 150% more cell divisions, until they are too worn-out (telomeres eventually become too diminished) tosustain any further cell division to replace dead cells. Topical use of magnesium-l-ascorbyl-phosphateprolongs the longevity of keratinacytes (skin cells) through an affect achieved by a slowdown of age-dependentshortening of telomeric DNA.
In essence, telomeres suffer from fewer DNA lesions due to the continuous and thoroughrepression of intracellular (inside the cell) reactive oxygen species (potent free radical form of oxidants) which wasrealized by magnesium ascorbyl-phosphate that exerted an antioxidant ability more persistent than ascorbic acid.
With the use of magnesium-l-ascorbyl-phosphate form of vitamin C: the cellular lifespan of cultivationof human skin epidermis keratinocytes (skin cells) was shown to be extended up to 150%. The lifespan-extended cells wereprevented from senescence-induced symptoms. They retained young cell morphological (shape and characteristics underthe microscope) aspects such as thick and compact shape and intense attachment to the culture substratum even upon advancedpopulation doubling levels, whereas other non-extended (untreated) cells looked thin or fibrous shape and large size uponreaching lower population doubling levels.
Magnesium-l-ascorbyl-phosphate is absorbed into the skin where it is continuously and safely convertedinto ascorbic acid (vitamin C).
It is NOT acidic like l-ascorbic acid, which stings and burns skin, and is aserious danger to your eyes. Pretreatment with magnesium-l-ascorbyl-phosphate significantly prevented such photo-damageas sunburn cell formation, DNA fragmentation and lipid (fatty compounds such as cell membranes) peroxidation whichwere caused by a single dose of UV-B irradiation. These results (of this study) suggest that the protective effect ofmagnesium-l-ascorbyl-phosphate on UV-B-induced cutaneous (skin) damage is due to the maintenance of a normal ascorbic acidlevel by conversion of magnesium-l-ascorbyl-phosphate to ascorbic acid in skin tissue.
The concentration of magnesiuml-ascorbyl-phosphate needed for this specific benefit is what is found in all of the DermCareMD anti aging skin care products and treatments.
Can ascorbic acid itself applied topically to skin protect against UV-B irradiation? No. In this study,ascorbic acid could not inhibit cytotoxicity (cell damage), but magnesium-l-ascorbyl-phosphate (MAP) was able to cancel theharmful effect of UV-B [emphasis added]. The topical concentration (dose) of magnesium-l-ascorbylphosphateneeded is in the DermCareMD anti aging skin care products and treatments.
Vitamin C comes in a number of forms. Of these, magnesium-l-ascorbyl-phosphate, or MAP, is the most effective, stable and skin-healthy of all forms of the vitamin.
Magnesium-L-Ascorbyl-Phosphate
• Increases of the longevity of skin cells by 150%.
• Is a potent antioxidant and inhibits lipid (fat) peroxidation unlike ascorbyl palmitate (c-ester, ester-c)that causes lipid peroxidation and kills skin cells when topically applied to skin and exposed tosunlight.
• Increases glucosaminoglycan (GAG: including collagen and hyaluronic acid) synthesis.
• Protects against harm caused by UV-B radiation.
• Is 1000 times less acid than ascorbic acid, vitamin C.
• Is very stable long-term, unlike ascorbic acid.• Safe and non-irritating; it has been used on the eye to heal corneal ulcers.
• Reduces skin hyperpigmentation (liver spots).
• Increases longevity of skin cells 150%
That sounds like science fiction! But it is real, and available now. Let us explain.It starts with your chromosomes. The 23 pairs of chromosomes contain all your 30,000+ genes. Eachchromosome is made up of two mirror image strands that have the appearance of a twisted ladder. There arefour different nucleic acids (two pairs); one mates only with its mirror image from the pair in thecorresponding site of that gene, on the other parallel ladder strand of DNA.
When a cell divides, each strand of each of the 23 pairs of chromosomes separate like an open zipper. This biological process is called mitosis. As the cell divides in half, 23 pairs of single stranded ("unzipped")chromosomes go into each new "daughter cell". To complete this process, each "unzipped" chromosomerecreates its missing mirror image strand by the "mating" with each nucleic acid of its counterpart, buildingthe missing side of the parallel strand of DNA for that chromosome.
Now you have a fully functioning cell, almost, except that the exposed ends of each chromosome become frayed after dividing and little pieces break off witheach of the cell divisions. The exposed ends of each chromosome are called telomeres. Genes are lost withthese tiny fragments at each cell division. This eventually limits the number of cell to the point where itcannot sustain further divisions and remain alive. This has been referred to as Hayflick's Limit called loss ofproliferation ability and premature senescence, and it is a serious undisclosed danger of all methods of skinexfoliation.
Magnesium-L-Ascorbyl-Phosphate
With the topical use of magnesium-l-ascorbyl-phosphate form of vitamin C (found in all of the DermCareMD anti aging skin care products and treatments), the telomeres can survive,allowing for 150% more cell divisions, until they are too worn-out (telomeres eventually become too diminished) tosustain any further cell division to replace dead cells. Topical use of magnesium-l-ascorbyl-phosphateprolongs the longevity of keratinacytes (skin cells) through an affect achieved by a slowdown of age-dependentshortening of telomeric DNA.
In essence, telomeres suffer from fewer DNA lesions due to the continuous and thoroughrepression of intracellular (inside the cell) reactive oxygen species (potent free radical form of oxidants) which wasrealized by magnesium ascorbyl-phosphate that exerted an antioxidant ability more persistent than ascorbic acid.
With the use of magnesium-l-ascorbyl-phosphate form of vitamin C: the cellular lifespan of cultivationof human skin epidermis keratinocytes (skin cells) was shown to be extended up to 150%. The lifespan-extended cells wereprevented from senescence-induced symptoms. They retained young cell morphological (shape and characteristics underthe microscope) aspects such as thick and compact shape and intense attachment to the culture substratum even upon advancedpopulation doubling levels, whereas other non-extended (untreated) cells looked thin or fibrous shape and large size uponreaching lower population doubling levels.
Magnesium-l-ascorbyl-phosphate is absorbed into the skin where it is continuously and safely convertedinto ascorbic acid (vitamin C).
It is NOT acidic like l-ascorbic acid, which stings and burns skin, and is aserious danger to your eyes. Pretreatment with magnesium-l-ascorbyl-phosphate significantly prevented such photo-damageas sunburn cell formation, DNA fragmentation and lipid (fatty compounds such as cell membranes) peroxidation whichwere caused by a single dose of UV-B irradiation. These results (of this study) suggest that the protective effect ofmagnesium-l-ascorbyl-phosphate on UV-B-induced cutaneous (skin) damage is due to the maintenance of a normal ascorbic acidlevel by conversion of magnesium-l-ascorbyl-phosphate to ascorbic acid in skin tissue.
The concentration of magnesiuml-ascorbyl-phosphate needed for this specific benefit is what is found in all of the DermCareMD anti aging skin care products and treatments.
Can ascorbic acid itself applied topically to skin protect against UV-B irradiation? No. In this study,ascorbic acid could not inhibit cytotoxicity (cell damage), but magnesium-l-ascorbyl-phosphate (MAP) was able to cancel theharmful effect of UV-B [emphasis added]. The topical concentration (dose) of magnesium-l-ascorbylphosphateneeded is in the DermCareMD anti aging skin care products and treatments.
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