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Wednesday, December 19, 2007

The Power of Grape Seed Extract in DermCareMD Products and Treatments

Grape seed extract is a powerful antioxidant that protects the body from premature aging, disease and decay.

Grape seed extract: helps protect your skin by:• Promoting youthful skin, cell health, elasticity, and flexibility.• Providing 20 times the antioxidant power of vitamin C.• Providing antioxidant protection leading to thicker, healthier skin.• Preventing wrinkles and skin cancer.• Protecting microscopic blood vessels in skin.• Stimulating hair follicles.

Grape seed extract is known as a powerful antioxidant that protects the body from premature aging, disease and decay.The healthful, biologically active compounds that grape seeds contain are mainly phenols such as proanthocyanidins (oligomericproanthocyanidins*). Scientific studies have shown that the antioxidant power of proanthocyanidins is 20 times greater thanvitamin C.

Extensive research suggests that grape seed extract is beneficial in many areas of health because of itsantioxidant effect to bond with collagen, promoting youthful skin, cell health, elasticity, and flexibility. Otherstudies have shown that proanthocyanidins help to protect skin from sun damage to prevent wrinkles andskin cancer to improve vision, to improve flexibility in joints, arteries, and body tissues such as the heart, and to improve blood circulationby strengthening capillaries, arteries and veins.

Now that we have introduced you to the power of grape seed extract, let us share some of the recentresearch revealing its protection against skin cancer.

Grape Seed Extract kills skin cancer cells. Grape seed proanthocyanidins have been shown to inhibit skin chemical carcinogenesis and photo-carcinogenesis. In thisstudy, doctors at the University of Alabama Department of Dermatology documented that grape seed proanthocyanidins kill skin cancer cells (induce apoptosis) by increasing the expression (activity) of tumorsuppressorProtein 53, while the anti-apoptotic (sparing cancer cell) proteins Bcl-2 and Bcl-l, were downregulated(decreased in activity),whereas the expression of the pro-apoptotic (cancer cell-killing) protein, Bax, (and seven assistingfactors that destroy cancer cells) were markedly increased.

Can you imagine the hundreds of thousands of pounds of grape seeds discarded as waste in theproduction of wine and grape juice? Now research has shown that nature has the potential to keep your skinyouthful while reversing signs of aging and disease-producing damaged. In addition to skin benefits, all theother benefits of grape seed extract and many other health protecting ingredients, available through the world’s best researched and formulatedproducts DermcareMD.

Also, this ingredient possesses high anti-tumor and antioxidant properties & prevents skin aging.

Four doctors at the prestigious AMC Cancer Research Center in Denver who participated in manystudies of the healthful benefits of grape seed extract reported: "Proanthocyanidins present in grape seeds are knownto exert anti-inflammatory, anti-arthritic and anti-allergic activities, prevent skin aging, scavenge oxygen free radicals and inhibitUV radiation-induced peroxidation activity." Since most of these events are associated with the tumor promotion stage ofcarcinogenesis, these studies suggest that grape seed polyphenols and the procyanidins present therein could be anti-carcinogenicand/or anti-tumor-promoting agents.
These researchers applied potent carcinogens to the skin of mice and noted "a highly significantinhibition of TPA (carcinogen) tumor promotion. he observed anti-tumor-promoting effects of grape seed polyphenols weredose-dependent and were evident in terms of a reduction in tumor incidence (60% inhibition), tumor multiplicity (83%inhibition) and tumor volume (87% inhibition)." As they stated: "[t]aken together, for the first time* these results showthat grape seed polyphenols possess high anti-tumor-promoting activity due to the strong antioxidant effect of procyanidins presenttherein."

Based on the concentration of grape seed extract that these doctors used, and skin surface area coveredin the above research, we have selected the optimum concentration of grape seed extract for the DermCareMD products.

Blocks cancer-causing enzymes -- Grape seed extract polyphenols were shown to block the cancer-causing enzymes ornithinedecarboxylase and myeloperoxidase. "The final number of tumors per mouse in the grape seed extract polyphenol treatedanimals was decreased 94%." Antioxidant protection leads to thicker, healthier outer skin The topical use of grape seed extracts and other antioxidants (all in our DermCareMD products), "induced morphological (shape) changes leading to a thicker epidermallayer providing evidence of the positive effects of the treatment on the viability of the keratinocytes (outer layer skin cells) afterUV-A irradiation."
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